STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MPDU1Mannose-P-dolichol utilization defect 1. (138 aa)    
Predicted Functional Partners:
MPPE1
Metallophosphoesterase 1.
      
 0.690
ENSSBOP00000021263
Phosphatidylinositol-glycan biosynthesis class W protein; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
      
 0.690
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
      
 0.681
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
      
 0.681
DPM1
Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
   
  
 0.660
PIGB
Mannosyltransferase.
      
 0.654
PIGL
Phosphatidylinositol glycan anchor biosynthesis class L.
      
 0.653
PIGH
Phosphatidylinositol glycan anchor biosynthesis class H.
      
 0.653
PIGC
Phosphatidylinositol glycan anchor biosynthesis class C.
      
 0.653
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
      
 0.653
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.