STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHCGRh family C glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (479 aa)    
Predicted Functional Partners:
HYAL3
Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family.
   
  
 0.622
SPAM1
Hyaluronidase.
   
  
 0.568
HYAL4
Hyaluronidase.
   
  
 0.568
HYAL1
Hyaluronidase.
   
  
 0.532
AP5S1
Adaptor related protein complex 5 subunit sigma 1.
      
 0.521
ENSSBOP00000027083
Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
  
 
0.508
AQP1
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.506
TICRR
TOPBP1 interacting checkpoint and replication regulator.
      
 0.491
SPTA1
Spectrin alpha, erythrocytic 1.
   
  
 0.477
HYAL2
Hyaluronidase.
   
  
 0.472
Your Current Organism:
Saimiri boliviensis
NCBI taxonomy Id: 39432
Other names: Bolivian squirrel monkey, S. boliviensis boliviensis, Saimiri boliviensis boliviensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.