node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCD1 | ELOVL1 | ENSSBOP00000016558 | ENSSBOP00000040561 | ATP binding cassette subfamily D member 1. | Elongation of very long chain fatty acids protein. | 0.576 |
ABCD1 | PEX7 | ENSSBOP00000016558 | ENSSBOP00000025330 | ATP binding cassette subfamily D member 1. | Peroxisomal biogenesis factor 7. | 0.562 |
CERS2 | CERS3 | ENSSBOP00000034934 | ENSSBOP00000016293 | Ceramide synthase 2. | Ceramide synthase 3. | 0.902 |
CERS2 | ELOVL1 | ENSSBOP00000034934 | ENSSBOP00000040561 | Ceramide synthase 2. | Elongation of very long chain fatty acids protein. | 0.644 |
CERS3 | CERS2 | ENSSBOP00000016293 | ENSSBOP00000034934 | Ceramide synthase 3. | Ceramide synthase 2. | 0.902 |
CERS3 | ELOVL1 | ENSSBOP00000016293 | ENSSBOP00000040561 | Ceramide synthase 3. | Elongation of very long chain fatty acids protein. | 0.535 |
ELOVL1 | ABCD1 | ENSSBOP00000040561 | ENSSBOP00000016558 | Elongation of very long chain fatty acids protein. | ATP binding cassette subfamily D member 1. | 0.576 |
ELOVL1 | CERS2 | ENSSBOP00000040561 | ENSSBOP00000034934 | Elongation of very long chain fatty acids protein. | Ceramide synthase 2. | 0.644 |
ELOVL1 | CERS3 | ENSSBOP00000040561 | ENSSBOP00000016293 | Elongation of very long chain fatty acids protein. | Ceramide synthase 3. | 0.535 |
ELOVL1 | ELOVL3 | ENSSBOP00000040561 | ENSSBOP00000024185 | Elongation of very long chain fatty acids protein. | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | 0.929 |
ELOVL1 | ELOVL4 | ENSSBOP00000040561 | ENSSBOP00000038003 | Elongation of very long chain fatty acids protein. | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] | 0.916 |
ELOVL1 | ELOVL7 | ENSSBOP00000040561 | ENSSBOP00000032186 | Elongation of very long chain fatty acids protein. | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] | 0.901 |
ELOVL1 | HSD17B12 | ENSSBOP00000040561 | ENSSBOP00000013876 | Elongation of very long chain fatty acids protein. | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.935 |
ELOVL1 | MED16 | ENSSBOP00000040561 | ENSSBOP00000004091 | Elongation of very long chain fatty acids protein. | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.454 |
ELOVL1 | PEX7 | ENSSBOP00000040561 | ENSSBOP00000025330 | Elongation of very long chain fatty acids protein. | Peroxisomal biogenesis factor 7. | 0.529 |
ELOVL1 | SORBS3 | ENSSBOP00000040561 | ENSSBOP00000009726 | Elongation of very long chain fatty acids protein. | Sorbin and SH3 domain containing 3. | 0.465 |
ELOVL3 | ELOVL1 | ENSSBOP00000024185 | ENSSBOP00000040561 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | Elongation of very long chain fatty acids protein. | 0.929 |
ELOVL3 | ELOVL7 | ENSSBOP00000024185 | ENSSBOP00000032186 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] | 0.929 |
ELOVL3 | HSD17B12 | ENSSBOP00000024185 | ENSSBOP00000013876 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.918 |
ELOVL4 | ELOVL1 | ENSSBOP00000038003 | ENSSBOP00000040561 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] | Elongation of very long chain fatty acids protein. | 0.916 |