Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0020PFAM: protein of unknown function DUF1021; KEGG: cth:Cthe_2401 hypothetical protein. (88 aa)    
Predicted Functional Partners:
Ccel_3095
Purine operon repressor, PurR; TIGRFAM: pur operon repressor; PFAM: phosphoribosyltransferase; purine repressor; KEGG: cth:Cthe_2627 purine operon repressor.
 
     0.551
Ccel_0021
PFAM: Peptidoglycan-binding LysM; KEGG: cth:Cthe_2402 peptidoglycan-binding LysM.
       0.536
Ccel_0019
Hypothetical protein; KEGG: cbt:CLH_0458 sporulation peptidase YabG.
       0.508
Ccel_0080
Phosphoesterase RecJ domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family.
 
    0.502
Ccel_0091
KEGG: cth:Cthe_2247 regulatory protein, MerR.
  
     0.450
ispE
4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
       0.423
Ccel_1321
PFAM: protein of unknown function DUF464; KEGG: cth:Cthe_0161 hypothetical protein.
  
     0.400
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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