Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0031PFAM: metallophosphoesterase; KEGG: cth:Cthe_2411 metallophosphoesterase. (379 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.971
Ccel_0032
Conserved hypothetical protein; KEGG: cth:Cthe_2412 SMC protein-like protein.
 
 
 0.956
Ccel_0052
PFAM: SMC domain protein; KEGG: ctc:CTC00579 exonuclease SbcC.
  
 0.798
Ccel_0065
PFAM: SMC domain protein; KEGG: sun:SUN_0732 hypothetical protein.
  
 0.798
Ccel_2709
PFAM: SMC domain protein; KEGG: chu:CHU_0040 ATPase involved in DNA repair.
  
 0.798
Ccel_3310
PFAM: SMC domain protein; KEGG: spj:MGAS2096_Spy0560 chromosome segregation ATPases.
  
 0.798
acpS
Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.704
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.635
Ccel_0029
Hypothetical protein; KEGG: hau:Haur_4114 multi-sensor signal transduction histidine kinase.
       0.625
Ccel_0033
PFAM: NLP/P60 protein; SH3 type 3 domain protein; KEGG: cth:Cthe_2413 NLP/P60.
       0.574
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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