STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0041PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. (337 aa)    
Predicted Functional Partners:
Ccel_0042
TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: cth:Cthe_2419 DNA replication protein DnaD.
 
  
 0.947
Ccel_0082
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.886
Ccel_1326
KEGG: cth:Cthe_0165 hypothetical protein.
  
     0.753
Ccel_3341
KEGG: cth:Cthe_2072 hypothetical protein.
  
     0.662
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.611
Ccel_3329
PFAM: helix-hairpin-helix motif; 8-oxoguanine DNA glycosylase domain protein; SMART: HhH-GPD family protein; KEGG: cth:Cthe_2068 8-oxoguanine DNA glycosylase-like protein.
  
     0.593
Ccel_1522
PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cth:Cthe_0559 single-strand DNA-binding protein.
 
   
 0.554
Ccel_0534
PFAM: Radical SAM domain protein; KEGG: cth:Cthe_0906 radical SAM family protein.
  
     0.537
Ccel_1879
KEGG: cth:Cthe_1275 H+-ATPase subunit H.
  
     0.533
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
    
 
 0.517
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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