| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ccel_0002 | Ccel_0041 | Ccel_0002 | Ccel_0041 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | 0.513 |
| Ccel_0002 | Ccel_0082 | Ccel_0002 | Ccel_0082 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.598 |
| Ccel_0002 | Ccel_1522 | Ccel_0002 | Ccel_1522 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cth:Cthe_0559 single-strand DNA-binding protein. | 0.400 |
| Ccel_0002 | polA | Ccel_0002 | Ccel_2075 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.991 |
| Ccel_0041 | Ccel_0002 | Ccel_0041 | Ccel_0002 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.513 |
| Ccel_0041 | Ccel_0042 | Ccel_0041 | Ccel_0042 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: cth:Cthe_2419 DNA replication protein DnaD. | 0.946 |
| Ccel_0041 | Ccel_0082 | Ccel_0041 | Ccel_0082 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.907 |
| Ccel_0041 | Ccel_0534 | Ccel_0041 | Ccel_0534 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | PFAM: Radical SAM domain protein; KEGG: cth:Cthe_0906 radical SAM family protein. | 0.537 |
| Ccel_0041 | Ccel_1326 | Ccel_0041 | Ccel_1326 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | KEGG: cth:Cthe_0165 hypothetical protein. | 0.753 |
| Ccel_0041 | Ccel_1522 | Ccel_0041 | Ccel_1522 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cth:Cthe_0559 single-strand DNA-binding protein. | 0.539 |
| Ccel_0041 | Ccel_1879 | Ccel_0041 | Ccel_1879 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | KEGG: cth:Cthe_1275 H+-ATPase subunit H. | 0.533 |
| Ccel_0041 | Ccel_3329 | Ccel_0041 | Ccel_3329 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | PFAM: helix-hairpin-helix motif; 8-oxoguanine DNA glycosylase domain protein; SMART: HhH-GPD family protein; KEGG: cth:Cthe_2068 8-oxoguanine DNA glycosylase-like protein. | 0.593 |
| Ccel_0041 | Ccel_3341 | Ccel_0041 | Ccel_3341 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | KEGG: cth:Cthe_2072 hypothetical protein. | 0.662 |
| Ccel_0041 | polA | Ccel_0041 | Ccel_2075 | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.616 |
| Ccel_0042 | Ccel_0041 | Ccel_0042 | Ccel_0041 | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: cth:Cthe_2419 DNA replication protein DnaD. | PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC. | 0.946 |
| Ccel_0042 | Ccel_1326 | Ccel_0042 | Ccel_1326 | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: cth:Cthe_2419 DNA replication protein DnaD. | KEGG: cth:Cthe_0165 hypothetical protein. | 0.752 |
| Ccel_0042 | Ccel_1522 | Ccel_0042 | Ccel_1522 | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: cth:Cthe_2419 DNA replication protein DnaD. | PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cth:Cthe_0559 single-strand DNA-binding protein. | 0.422 |
| Ccel_0042 | Ccel_3329 | Ccel_0042 | Ccel_3329 | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: cth:Cthe_2419 DNA replication protein DnaD. | PFAM: helix-hairpin-helix motif; 8-oxoguanine DNA glycosylase domain protein; SMART: HhH-GPD family protein; KEGG: cth:Cthe_2068 8-oxoguanine DNA glycosylase-like protein. | 0.534 |
| Ccel_0042 | Ccel_3341 | Ccel_0042 | Ccel_3341 | TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: cth:Cthe_2419 DNA replication protein DnaD. | KEGG: cth:Cthe_2072 hypothetical protein. | 0.663 |
| Ccel_0082 | Ccel_0002 | Ccel_0082 | Ccel_0002 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.598 |