Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Ccel_0066PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: nwi:Nwi_2131 DEAD/DEAH box helicase. (1100 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
  0.633
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.630
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.626
Ccel_0660
PFAM: DEAD_2 domain protein; SMART: Helicase-like, DEXD box c2 type; helicase c2; KEGG: cth:Cthe_0289 DEAD_2.
   
 0.557
Ccel_2717
KEGG: btl:BALH_0835 hypothetical protein.
   
 0.557
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 0.555
Ccel_1655
PFAM: cellulosome protein dockerin type I; KEGG: sus:Acid_0258 hypothetical protein.
  
   
 0.536
Ccel_0065
PFAM: SMC domain protein; KEGG: sun:SUN_0732 hypothetical protein.
  
  
 0.484
Ccel_0029
Hypothetical protein; KEGG: hau:Haur_4114 multi-sensor signal transduction histidine kinase.
  
     0.450
Ccel_0067
PFAM: integrase family protein; KEGG: cbl:CLK_1309 site-specific recombinase; Belongs to the 'phage' integrase family.
  
    0.445
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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