Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0072KEGG: abm:ABSDF3536 hypothetical protein. (838 aa)    
Predicted Functional Partners:
Ccel_1637
Hypothetical protein; KEGG: cth:Cthe_0351 PpiC-type peptidyl-prolyl cis-trans isomerase.
   
 
 0.575
Ccel_0492
PFAM: heat shock protein Hsp90; ATP-binding region ATPase domain protein; KEGG: cth:Cthe_0550 heat shock protein 90.
   
 0.548
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.525
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.498
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.455
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.450
Ccel_0705
KEGG: pdi:BDI_2301 pantothenate kinase.
    
   0.423
Ccel_0354
PFAM: RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; KEGG: cth:Cthe_1955 RNA binding S1.
    
 
 0.421
Ccel_0071
PFAM: SEC-C motif domain protein; KEGG: cth:Cthe_1113 SecC motif-containing protein.
       0.413
Ccel_0333
PFAM: glycosyl transferase family 2; KEGG: cth:Cthe_1788 glycosyl transferase family protein.
  
 
 0.409
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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