Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pheAPFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: cth:Cthe_2260 prephenate dehydratase. (280 aa)    
Predicted Functional Partners:
Ccel_1618
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: Chorismate mutase; DAHP synthetase I/KDSA; KEGG: lin:lin1641 bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase.
 
 
 0.985
Ccel_2881
Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: cth:Cthe_1796 prephenate dehydrogenase.
 
 0.972
Ccel_1965
PFAM: aminotransferase class I and II; KEGG: cno:NT01CX_0284 aspartate aminotransferase.
 
 
 0.957
Ccel_1451
PFAM: amino acid-binding ACT domain protein; KEGG: cth:Cthe_1377 hypothetical protein; Belongs to the UPF0735 family.
  
 
 0.955
hisC
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class V; aminotransferase class I and II; KEGG: cth:Cthe_2883 histidinol phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
 
 
 0.932
Ccel_1042
PFAM: aminotransferase class I and II; KEGG: cdf:CD1549 putative histidinol-phosphate aminotransferase.
 
 
 0.921
Ccel_1730
Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis.
    
 0.913
Ccel_2208
Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: cpr:CPR_0701 aspartate aminotransferase.
 
  
 0.894
Ccel_0659
PFAM: GCN5-related N-acetyltransferase; KEGG: cbf:CLI_3229 acetyltransferase.
    
  0.801
Ccel_2880
TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; KEGG: cth:Cthe_1795 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase.
 
  
 0.769
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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