Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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fliWProtein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum. (148 aa)    
Predicted Functional Partners:
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
 
 
 0.998
Ccel_0096
TIGRFAM: flagellar hook-associated protein 3; PFAM: flagellin domain protein; KEGG: cth:Cthe_2242 flagellar hook-associated protein FlgL.
 
 
 0.956
Ccel_0104
PFAM: flagellar protein FlaG protein; KEGG: cth:Cthe_2219 flagellar protein FlaG protein.
 
  
 0.949
Ccel_0106
PFAM: flagellar protein FliS; KEGG: cth:Cthe_2217 flagellar protein FliS.
 
  
 0.923
Ccel_2039
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: cth:Cthe_0477 flagellar motor switch protein FliM.
 
  
 0.904
Ccel_0105
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.903
Ccel_0100
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.898
Ccel_2038
CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: cth:Cthe_0478 flagellar motor switch protein.
 
  
 0.888
flgK
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cth:Cthe_2243 flagellar hook-associated protein FlgK.
 
  
 0.869
Ccel_0101
Flagellin domain protein; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.866
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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