Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0104PFAM: flagellar protein FlaG protein; KEGG: cth:Cthe_2219 flagellar protein FlaG protein. (128 aa)    
Predicted Functional Partners:
Ccel_0105
Flagellar hook-associated 2 domain protein; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
  
 0.991
Ccel_0106
PFAM: flagellar protein FliS; KEGG: cth:Cthe_2217 flagellar protein FliS.
 
  
 0.979
Ccel_2038
CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: cth:Cthe_0478 flagellar motor switch protein.
 
  
 0.972
fliW
Protein of unknown function DUF180; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
  
 0.949
Ccel_2039
PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; KEGG: cth:Cthe_0477 flagellar motor switch protein FliM.
 
  
 0.929
Ccel_2006
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.878
Ccel_2025
PFAM: CheC domain protein; KEGG: cth:Cthe_0492 CheC, inhibitor of MCP methylation.
 
    0.809
flgK
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cth:Cthe_2243 flagellar hook-associated protein FlgK.
 
  
 0.769
Ccel_2049
PFAM: flagellar assembly protein FliH; KEGG: cth:Cthe_0467 flagellar biosynthesis/type III secretory pathway protein-like protein.
 
  
 0.763
Ccel_0348
PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; KEGG: cth:Cthe_1961 nucleotidyl transferase.
   
   0.753
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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