Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0139PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: mta:Moth_0429 mannitol dehydrogenase. (537 aa)    
Predicted Functional Partners:
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
 
 0.994
uxuA-2
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
 
 0.983
uxaC
PFAM: Glucuronate isomerase; KEGG: bsu:BSU12300 glucuronate isomerase.
 
 
 0.975
uxaC-2
PFAM: Glucuronate isomerase; KEGG: csc:Csac_1949 glucuronate isomerase.
 
 
 0.974
Ccel_0141
PFAM: glycoside hydrolase family 67; glycosyl hydrolase 67 C-teriminal domain protein; Glycosyl hydrolase 67 middle domain protein; KEGG: gtn:GTNG_1770 alpha-glucuronidase; Belongs to the glycosyl hydrolase 67 family.
     
 0.733
Ccel_3193
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR domain protein; KEGG: cbe:Cbei_4085 transcriptional regulator, GntR family.
 
   
 0.652
tpiA
Phosphoglycerate kinase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
     
 0.471
Ccel_1675
TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: cpe:CPE0153 glucuronide permease.
 
   
 0.468
Ccel_1670
PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: cpe:CPE0147 beta-D-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
 
   
 0.465
Ccel_0138
PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: cth:Cthe_0344 malate dehydrogenase.
     
 0.432
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.