Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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Ccel_0174Protein of unknown function DUF710; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (145 aa)    
Predicted Functional Partners:
Ccel_0301
KEGG: cth:Cthe_2712 hypothetical protein.
 
  
 0.656
Ccel_0172
KEGG: cth:Cthe_2091 hypothetical protein.
 
   
 0.611
Ccel_1326
KEGG: cth:Cthe_0165 hypothetical protein.
  
     0.581
Ccel_1522
PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cth:Cthe_0559 single-strand DNA-binding protein.
  
   
 0.517
Ccel_0595
KEGG: cth:Cthe_0793 hypothetical protein.
  
     0.509
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 
 0.504
Ccel_0173
TIGRFAM: hemerythrin-like metal-binding protein; PFAM: Hemerythrin HHE cation binding domain protein; KEGG: gsu:GSU2929 hypothetical protein.
       0.497
Ccel_0175
PFAM: metalloenzyme domain protein; KEGG: cth:Cthe_2087 metalloenzyme.
       0.492
Ccel_0176
PFAM: peptidase U32; KEGG: cth:Cthe_2086 peptidase U32.
     
 0.492
csrA
Carbon storage regulator, CsrA; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
  
    0.487
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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