Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0179PFAM: NUDIX hydrolase; KEGG: aoe:Clos_1784 NUDIX hydrolase. (137 aa)    
Predicted Functional Partners:
Ccel_3341
KEGG: cth:Cthe_2072 hypothetical protein.
  
     0.662
Ccel_0172
KEGG: cth:Cthe_2091 hypothetical protein.
 
   
 0.621
Ccel_0279
PFAM: Protein of unknown function DUF1779; KEGG: cth:Cthe_2614 hypothetical protein.
  
     0.602
Ccel_0289
PFAM: S-layer domain protein; KEGG: cth:Cthe_1931 S-layer-like domain-containing protein.
  
     0.574
hflX
GTP-binding proten HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
       0.572
Ccel_0532
KEGG: cth:Cthe_0955 hypothetical protein.
  
     0.553
Ccel_0177
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
     
 0.538
Ccel_0180
PFAM: protein of unknown function UPF0029; Domain of unknown function DUF1949; KEGG: cth:Cthe_2078 hypothetical protein.
       0.529
Ccel_1326
KEGG: cth:Cthe_0165 hypothetical protein.
  
     0.516
Ccel_0041
PFAM: IstB domain protein ATP-binding protein; KEGG: cth:Cthe_2418 DNA replication protein DnaC.
  
     0.509
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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