STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0215PFAM: protein of unknown function DUF255; KEGG: cth:Cthe_0291 hypothetical protein. (673 aa)    
Predicted Functional Partners:
Ccel_0428
PFAM: S-layer domain protein; glycoside hydrolase family 5; Carbohydrate binding family 17/28; KEGG: csc:Csac_0678 cellulase.
   
   0.460
Ccel_0740
PFAM: glycoside hydrolase family 5; cellulosome protein dockerin type I; KEGG: cth:Cthe_2872 glycoside hydrolase family protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
   
   0.460
celCCD
Glycoside hydrolase family 5; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
   
   0.460
celCCA
Glycoside hydrolase family 5; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
   
   0.460
Ccel_2337
PFAM: glycoside hydrolase family 5; cellulosome protein dockerin type I; KEGG: cth:Cthe_0536 glycoside hydrolase family protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
   
   0.460
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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