Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0262PFAM: glycosyl transferase family 4; UDP-N-acetylglucosamine 2-epimerase; KEGG: cth:Cthe_2601 UDP-N-acetylglucosamine 2-epimerase. (762 aa)    
Predicted Functional Partners:
Ccel_2929
TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase NAD-binding; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: bat:BAS5120 UDP-N-acetyl-D-mannosamine dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
 0.992
Ccel_2921
Glycosyl transferase, WecB/TagA/CpsF family; Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid.
 
 
 0.989
Ccel_2807
TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: ckl:CKL_3169 polysaccharide biosynthesis protein.
 
  
 0.972
uppP
Bacitracin resistance protein BacA; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
 
  
 0.955
Ccel_1817
PFAM: polysaccharide biosynthesis protein; KEGG: mmz:MmarC7_1361 polysaccharide biosynthesis protein.
  
  
 0.903
Ccel_2616
PFAM: acyltransferase 3; KEGG: sgo:SGO_2012 transmembrane protein.
  
  
 0.903
Ccel_2883
PFAM: glycosyl transferase group 1; polysaccharide pyruvyl transferase; KEGG: cth:Cthe_2702 polysaccharide pyruvyl transferase.
 
  
 0.898
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 
 0.848
Ccel_0132
TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; RimK domain protein ATP-grasp; KEGG: cth:Cthe_2204 cyanophycin synthetase.
  
  
 0.841
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
 0.809
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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