STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0281TIGRFAM: SpoIID/LytB domain protein; stage II sporulation protein D; PFAM: Stage II sporulation D domain protein; KEGG: cth:Cthe_2616 SpoIID/LytB domain-containing protein. (341 aa)    
Predicted Functional Partners:
Ccel_1944
TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein; KEGG: cth:Cthe_1328 stage II sporulation P.
  
  
 0.795
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.744
Ccel_1916
TIGRFAM: stage III sporulation protein AA; SMART: AAA ATPase; KEGG: cth:Cthe_0845 stage III sporulation protein spoIIIAA.
  
  
 0.743
Ccel_0282
PFAM: Peptidase M23; KEGG: cth:Cthe_2617 peptidase M23B.
 
   
 0.713
Ccel_2986
KEGG: cth:Cthe_2681 serine phosphatase; TIGRFAM: stage II sporulation protein E; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
 
   
 0.672
Ccel_0292
TIGRFAM: stage II sporulation protein R; PFAM: Sporulation stage II protein R; KEGG: cth:Cthe_1920 stage II sporulation protein R.
  
   
 0.671
Ccel_0573
TIGRFAM: sporulation protein YqfD; PFAM: putative stage IV sporulation YqfD; KEGG: cth:Cthe_1072 putative stage IV sporulation YqfD.
  
  
 0.657
Ccel_1909
KEGG: cth:Cthe_0838 hypothetical protein.
  
  
 0.654
Ccel_1752
TIGRFAM: stage II sporulation protein M; PFAM: protein of unknown function DUF95 transmembrane; KEGG: cth:Cthe_0675 hypothetical protein.
  
   
 0.646
Ccel_2063
sigma-E processing peptidase SpoIIGA; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
   
 0.632
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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