Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0374TIGRFAM: beta-galactosidase; PFAM: glycoside hydrolase family 1; KEGG: amr:AM1_2790 beta-glucosidase. (450 aa)    
Predicted Functional Partners:
Ccel_2109
Glycosyltransferase 36; PFAM: putative carbohydrate binding; glycosyltransferase 36; glycosyltransferase 36 associated; KEGG: cth:Cthe_0275 cellobiose phosphorylase.
    
 0.908
Ccel_1179
TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: cno:NT01CX_1588 mannose-6-phosphate isomerase, class I.
 
  
 0.869
Ccel_1670
PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: cpe:CPE0147 beta-D-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
 
   
 0.755
celCCD
Glycoside hydrolase family 5; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
 
  
 0.718
Ccel_1139
PFAM: glycoside hydrolase family 3 domain protein; KEGG: cbe:Cbei_3765 glycoside hydrolase, family 3 domain protein.
    
 0.703
Ccel_2454
PFAM: glycoside hydrolase family 3 domain protein; KEGG: cpy:Cphy_0220 glycoside hydrolase family 3 protein; Belongs to the glycosyl hydrolase 3 family.
    
 0.703
Ccel_0373
TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA.
       0.701
Ccel_0203
PFAM: glycoside hydrolase family 3 domain protein; KEGG: cbe:Cbei_4974 glycoside hydrolase, family 3 domain protein.
    
 0.694
Ccel_3410
PFAM: glycoside hydrolase family 3 domain protein; KEGG: acl:ACL_0715 glycosyl hydrolase, family 3.
    
 0.694
celCCA
Glycoside hydrolase family 5; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
    
 0.690
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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