Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0378KEGG: dsy:DSY4421 hypothetical protein. (129 aa)    
Predicted Functional Partners:
Ccel_0377
KEGG: dsy:DSY4420 hypothetical protein.
 
    0.925
Ccel_0376
KEGG: dsy:DSY4419 hypothetical protein.
  
    0.721
Ccel_0375
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: dsy:DSY4418 hypothetical protein.
  
    0.719
Ccel_0812
Sigma 54 interacting domain protein; KEGG: cth:Cthe_2742 endopeptidase La; TIGRFAM: ATP-dependent protease LonB; PFAM: magnesium chelatase ChlI subunit; AAA ATPase central domain protein; peptidase S16 lon domain protein; SMART: AAA ATPase.
  
    0.561
Ccel_0374
TIGRFAM: beta-galactosidase; PFAM: glycoside hydrolase family 1; KEGG: amr:AM1_2790 beta-glucosidase.
       0.477
Ccel_0373
TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA.
       0.438
Ccel_1745
KEGG: cth:Cthe_0690 hypothetical protein.
  
    0.415
Ccel_0379
Protein of unknown function DUF291; PFAM: coagulation factor 5/8 type domain protein; glycoside hydrolase family 5; cellulosome protein dockerin type I; protein of unknown function DUF291; KEGG: cth:Cthe_0821 coagulation factor 5/8 type-like protein.
       0.403
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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