Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0399KEGG: cth:Cthe_2899 putative anti-sigma regulatory factor, serine/threonine protein kinase. (128 aa)    
Predicted Functional Partners:
Ccel_0398
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cth:Cthe_2898 anti-sigma-factor antagonist.
 
 
 0.998
Ccel_0400
TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: cth:Cthe_2900 RNA polymerase, sigma 28 subunit.
 
 
 0.988
Ccel_3361
KEGG: cth:Cthe_2166 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein.
 
 
 0.939
Ccel_2284
RNA polymerase, sigma 28 subunit, SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.897
Ccel_0013
KEGG: cth:Cthe_2385 hypothetical protein.
   
  
 0.771
Ccel_2286
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cth:Cthe_0118 anti-sigma-factor antagonist.
 
 
 0.740
Ccel_0264
PFAM: MotA/TolQ/ExbB proton channel; KEGG: csc:Csac_1524 MotA/TolQ/ExbB proton channel.
   
    0.724
Ccel_2046
KEGG: cth:Cthe_0470 hypothetical protein.
   
    0.724
Ccel_2050
TIGRFAM: flagellar motor switch protein FliG; KEGG: cth:Cthe_0466 flagellar motor switch protein G.
   
    0.724
Ccel_2054
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.724
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (24%) [HD]