Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0422PFAM: major facilitator superfamily MFS_1; KEGG: aoe:Clos_0840 major facilitator transporter. (410 aa)    
Predicted Functional Partners:
Ccel_0423
PFAM: VanW family protein; KEGG: aoe:Clos_0839 VanW family protein.
 
   
 0.693
Ccel_1118
PFAM: major facilitator superfamily MFS_1; KEGG: ckl:CKL_2256 transporter protein.
 
     0.561
Ccel_0424
PFAM: protein of unknown function DUF6 transmembrane; KEGG: swo:Swol_1359 hypothetical protein.
 
     0.485
Ccel_0421
Hypothetical protein.
       0.462
Ccel_2331
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; KEGG: bsu:BSU17180 polyketide synthase of type I.
  
  
 0.456
Ccel_2378
TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; condensation domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR domain protein; Beta-ketoacyl synthase; KEGG: bld:BLi00401 lichenysin synthetase A.
  
  
 0.449
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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