Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0462TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: gsu:GSU0306 hydrogenase maturation protein HypF. (790 aa)    
Predicted Functional Partners:
Ccel_0465
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: npu:Npun_R0359 hydrogenase expression/formation protein HypE.
 
 
 0.979
Ccel_0463
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: deb:DehaBAV1_1241 hydrogenase assembly chaperone HypC/HupF.
 
 
 0.962
Ccel_0464
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: cac:CAC0811 hydrogenase expression-formation factor (HypD).
 
  
 0.955
Ccel_1681
PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: cth:Cthe_1060 AIR synthase related protein-like protein.
 
 
 0.913
Ccel_3363
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: det:DET1431 hydrogenase accessory protein HypB.
 
   
 0.867
Ccel_1071
PFAM: nickel-dependent hydrogenase large subunit; KEGG: cbb:CLD_2800 [Ni/Fe] hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.862
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.849
Ccel_1070
TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: cbl:CLK_1224 [Ni/Fe] hydrogenase, small subunit.
 
 
 
 0.848
Ccel_1072
TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: cac:CA_P0143 hydrogenase maturation protease delta subunit, HyaD-like.
 
   
 0.744
Ccel_0461
TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: cth:Cthe_0987 riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family.
       0.718
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.