Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0474TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: cth:Cthe_0983 cell cycle protein; Belongs to the SEDS family. (378 aa)    
Predicted Functional Partners:
Ccel_2476
PFAM: penicillin-binding protein transpeptidase; KEGG: cac:CAC0506 penicillin-binding protein.
 
 0.961
Ccel_0482
TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family.
 
  
 
0.930
Ccel_2560
TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: cth:Cthe_0091 peptidoglycan glycosyltransferase.
 
 0.923
Ccel_0478
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase.
 
 0.920
Ccel_2477
PFAM: cell cycle protein; KEGG: cac:CAC0505 cell division membrane protein; Belongs to the SEDS family.
  
  
 
0.920
Ccel_1486
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: cth:Cthe_1011 peptidoglycan glycosyltransferase.
 
 0.897
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.827
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
 
 0.825
Ccel_2067
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
 
 0.824
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.812
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.