Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rsmHS-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (313 aa)    
Predicted Functional Partners:
mraZ
TIGRFAM: MraZ protein; PFAM: protein of unknown function UPF0040; KEGG: cth:Cthe_0982 MraZ protein; Belongs to the MraZ family.
  
 0.994
Ccel_0477
KEGG: cth:Cthe_0980 cell division protein FtsL.
  
  
 0.929
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
  
 
 0.760
murE
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.731
Ccel_0132
TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; RimK domain protein ATP-grasp; KEGG: cth:Cthe_2204 cyanophycin synthetase.
  
  
 0.704
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
   
 0.692
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: cbb:CLD_1411 phenylalanyl-tRNA synthetase, beta subunit.
 
  
 0.684
Ccel_0478
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase.
  
  
 0.679
rpsI
PFAM: ribosomal protein S9; KEGG: cth:Cthe_1782 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
 
 
 
 0.679
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.673
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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