Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0478PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. (734 aa)    
Predicted Functional Partners:
Ccel_2876
PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cth:Cthe_1760 1A family penicillin-binding protein.
 
 0.986
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.953
Ccel_1749
PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: cth:Cthe_0679 serine-type D-Ala-D-Ala carboxypeptidase.
 
 
 0.951
Ccel_0482
TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family.
 
 
 0.947
Ccel_1370
PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: cth:Cthe_1231 serine-type D-Ala-D-Ala carboxypeptidase.
 
 
 0.944
Ccel_0487
PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: cth:Cthe_3179 serine-type D-Ala-D-Ala carboxypeptidase.
 
 
 0.942
Ccel_0520
PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cth:Cthe_1171 serine-type D-Ala-D-Ala carboxypeptidase.
 
 
 0.942
murE
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
  
 0.939
Ccel_1486
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: cth:Cthe_1011 peptidoglycan glycosyltransferase.
 
  
0.932
Ccel_2560
TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: cth:Cthe_0091 peptidoglycan glycosyltransferase.
 
  
0.931
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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