| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ccel_0478 | Ccel_0482 | Ccel_0478 | Ccel_0482 | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family. | 0.951 |
| Ccel_0478 | mraY | Ccel_0478 | Ccel_0481 | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.925 |
| Ccel_0478 | murC | Ccel_0478 | Ccel_3096 | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.884 |
| Ccel_0478 | murD | Ccel_0478 | Ccel_1726 | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.879 |
| Ccel_0478 | murE | Ccel_0478 | Ccel_0479 | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.932 |
| Ccel_0478 | murF | Ccel_0478 | Ccel_0480 | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.955 |
| Ccel_0478 | murG | Ccel_0478 | Ccel_0483 | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.839 |
| Ccel_0482 | Ccel_0478 | Ccel_0482 | Ccel_0478 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family. | PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase. | 0.951 |
| Ccel_0482 | mraY | Ccel_0482 | Ccel_0481 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.928 |
| Ccel_0482 | murC | Ccel_0482 | Ccel_3096 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.801 |
| Ccel_0482 | murD | Ccel_0482 | Ccel_1726 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.801 |
| Ccel_0482 | murE | Ccel_0482 | Ccel_0479 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.807 |
| Ccel_0482 | murF | Ccel_0482 | Ccel_0480 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.903 |
| Ccel_0482 | murG | Ccel_0482 | Ccel_0483 | TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: cth:Cthe_0975 stage V sporulation protein E; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.965 |
| Ccel_1555 | Ccel_3348 | Ccel_1555 | Ccel_3348 | PFAM: phosphoesterase PA-phosphatase related; KEGG: tpd:Teth39_0213 phosphoesterase, PA-phosphatase related. | PFAM: phosphoesterase PA-phosphatase related; KEGG: cbt:CLH_3231 PAP2 family protein. | 0.922 |
| Ccel_1555 | mraY | Ccel_1555 | Ccel_0481 | PFAM: phosphoesterase PA-phosphatase related; KEGG: tpd:Teth39_0213 phosphoesterase, PA-phosphatase related. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.906 |
| Ccel_1555 | uppP | Ccel_1555 | Ccel_1147 | PFAM: phosphoesterase PA-phosphatase related; KEGG: tpd:Teth39_0213 phosphoesterase, PA-phosphatase related. | Bacitracin resistance protein BacA; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.915 |
| Ccel_3348 | Ccel_1555 | Ccel_3348 | Ccel_1555 | PFAM: phosphoesterase PA-phosphatase related; KEGG: cbt:CLH_3231 PAP2 family protein. | PFAM: phosphoesterase PA-phosphatase related; KEGG: tpd:Teth39_0213 phosphoesterase, PA-phosphatase related. | 0.922 |
| Ccel_3348 | mraY | Ccel_3348 | Ccel_0481 | PFAM: phosphoesterase PA-phosphatase related; KEGG: cbt:CLH_3231 PAP2 family protein. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.906 |
| Ccel_3348 | uppP | Ccel_3348 | Ccel_1147 | PFAM: phosphoesterase PA-phosphatase related; KEGG: cbt:CLH_3231 PAP2 family protein. | Bacitracin resistance protein BacA; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.915 |