Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0486PFAM: Monogalactosyldiacylglycerol synthase; KEGG: cth:Cthe_3177 monogalactosyldiacylglycerol synthase. (396 aa)    
Predicted Functional Partners:
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
 
 
 0.827
Ccel_0132
TIGRFAM: cyanophycin synthetase; PFAM: phosphoribosylglycinamide synthetase; cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; RimK domain protein ATP-grasp; KEGG: cth:Cthe_2204 cyanophycin synthetase.
  
 
 0.733
Ccel_2067
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
 
  
 0.719
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
  
 0.669
murC
UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.649
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
  
 0.646
Ccel_0262
PFAM: glycosyl transferase family 4; UDP-N-acetylglucosamine 2-epimerase; KEGG: cth:Cthe_2601 UDP-N-acetylglucosamine 2-epimerase.
  
  
 0.568
Ccel_2610
KEGG: oih:OB1131 hypothetical protein.
  
  
 0.538
Ccel_0487
PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: cth:Cthe_3179 serine-type D-Ala-D-Ala carboxypeptidase.
     
 0.491
Ccel_0474
TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: cth:Cthe_0983 cell cycle protein; Belongs to the SEDS family.
  
  
 0.412
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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