Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0495Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: cth:Cthe_0552 transcriptional regulator. (184 aa)    
Predicted Functional Partners:
Ccel_0494
PFAM: AMP-dependent synthetase and ligase; KEGG: cth:Cthe_0551 AMP-dependent synthetase and ligase.
 
   0.983
Ccel_1469
PFAM: AMP-dependent synthetase and ligase; KEGG: cth:Cthe_0551 AMP-dependent synthetase and ligase.
 
   0.932
Ccel_1862
PFAM: AMP-dependent synthetase and ligase; KEGG: csc:Csac_0934 AMP-dependent synthetase and ligase.
 
    0.676
Ccel_1868
PFAM: cyclase family protein; KEGG: amt:Amet_4419 cyclase family protein.
  
    0.648
Ccel_0888
Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; KEGG: cno:NT01CX_1225 DNA-binding protein, putative.
 
   
 0.623
Ccel_0565
PFAM: peptidase M24; KEGG: pca:Pcar_2614 Xaa-Pro aminopeptidase.
 
     0.499
Ccel_0553
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cth:Cthe_0867 2-oxoglutarate ferredoxin oxidoreductase, delta subunit.
  
     0.417
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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