Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Ccel_0533KEGG: amt:Amet_2345 hypothetical protein. (46 aa)    
Predicted Functional Partners:
Ccel_0534
PFAM: Radical SAM domain protein; KEGG: cth:Cthe_0906 radical SAM family protein.
 
 
   0.981
Ccel_2370
PFAM: Radical SAM domain protein; KEGG: cbf:CLI_3234 radical SAM domain-containing protein.
 
 
   0.749
Ccel_0328
PFAM: Radical SAM domain protein; KEGG: cpy:Cphy_2677 radical SAM domain-containing protein.
 
 
   0.745
Ccel_2600
PFAM: Radical SAM domain protein; KEGG: cbf:CLI_3234 radical SAM domain-containing protein.
 
 
   0.727
Ccel_0532
KEGG: cth:Cthe_0955 hypothetical protein.
       0.644
Ccel_0535
PFAM: transferase hexapeptide repeat containing protein; KEGG: tpd:Teth39_1022 carbonic anhydrase.
       0.581
Ccel_0531
TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: csc:Csac_0272 preprotein translocase, YajC subunit.
       0.513
tgt
Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...]
       0.455
secD
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.435
secF
Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.435
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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