Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0560Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: spj:MGAS2096_Spy1107 two-component system histidine kinase. (341 aa)    
Predicted Functional Partners:
Ccel_0559
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cdf:CD1957 two-component response regulator.
 
 
 0.960
Ccel_0558
PFAM: protein of unknown function DUF214; KEGG: ckl:CKL_3391 hypothetical protein.
 
   
 0.905
Ccel_0557
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ckl:CKL_3392 hypothetical protein.
 
   
 0.858
Ccel_0916
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ckl:CKL_1682 transcriptional regulator.
 
 
 0.828
Ccel_2324
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbk:CLL_A1406 regulatory protein VanR.
 
 
 0.825
Ccel_1157
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: ckl:CKL_0966 transcriptional regulator.
 
 
 0.824
Ccel_1153
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbf:CLI_0872 DNA-binding response regulator.
 
 
 0.822
Ccel_2658
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbk:CLL_A1387 regulatory protein VanR.
 
 
 0.819
Ccel_1714
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cth:Cthe_1847 two component transcriptional regulator.
 
 
 0.797
Ccel_2250
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cbf:CLI_0424 DNA-binding response regulator.
 
 
 0.796
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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