Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0575KEGG: cth:Cthe_1070 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; metal-dependent phosphohydrolase 7TM intracellular region; SMART: metal-dependent phosphohydrolase HD region. (745 aa)    
Predicted Functional Partners:
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.851
Ccel_0577
PFAM: diacylglycerol kinase; KEGG: cbt:CLH_0872 diacylglycerol kinase/PAP2 family protein.
 
     0.822
Ccel_0574
PFAM: PhoH family protein; KEGG: cth:Cthe_1071 PhoH-like protein.
     
 0.774
Ccel_0573
TIGRFAM: sporulation protein YqfD; PFAM: putative stage IV sporulation YqfD; KEGG: cth:Cthe_1072 putative stage IV sporulation YqfD.
       0.763
Ccel_0578
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
       0.746
era
GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
       0.700
Ccel_0572
TIGRFAM: sporulation protein YqfC; PFAM: protein of unknown function DUF1429; KEGG: cth:Cthe_1073 hypothetical protein.
       0.685
Ccel_0571
PFAM: polysaccharide deacetylase; KEGG: cth:Cthe_1074 polysaccharide deacetylase.
       0.540
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
       0.539
Ccel_0582
Phospholipase D/Transphosphatidylase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
 
     0.489
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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