Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0601PFAM: cell divisionFtsK/SpoIIIE; KEGG: cth:Cthe_1095 cell divisionFtsK/SpoIIIE. (838 aa)    
Predicted Functional Partners:
Ccel_0008
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cth:Cthe_2378 chromosome segregation DNA-binding protein; Belongs to the ParB family.
  
  
 0.806
Ccel_3483
TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cth:Cthe_2362 ParB family protein; Belongs to the ParB family.
  
  
 0.723
Ccel_2067
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
   
 
 0.711
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
 
  
 0.692
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.688
sepF
Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
     
 0.613
Ccel_2981
PFAM: integrase family protein; KEGG: pth:PTH_2135 integrase; Belongs to the 'phage' integrase family.
  
   
 0.597
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
  
  
 0.583
Ccel_0478
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cth:Cthe_0979 peptidoglycan glycosyltransferase.
 
 
 
 0.582
Ccel_0600
PFAM: DivIVA family protein; KEGG: cth:Cthe_0788 hypothetical protein.
     
 0.563
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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