Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0640KEGG: tex:Teth514_2337 hypothetical protein. (279 aa)    
Predicted Functional Partners:
Ccel_0639
KEGG: csc:Csac_0382 DNA repair photolyase-like protein.
 
   
 0.951
Ccel_0638
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ckl:CKL_2395 short-chain dehydrogenases/reductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.933
Ccel_2474
PFAM: methylenetetrahydrofolate reductase; homocysteine S-methyltransferase; KEGG: ckl:CKL_1762 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein.
     
 0.569
Ccel_2411
KEGG: tte:TTE1265 hypothetical protein.
 
     0.503
Ccel_0641
KEGG: cpy:Cphy_1776 hypothetical protein.
       0.433
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.432
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.423
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
     
 0.415
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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