Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Ccel_0664KEGG: cth:Cthe_0851 hypothetical protein. (88 aa)    
Predicted Functional Partners:
Ccel_0090
PFAM: phosphoribosyltransferase; KEGG: cth:Cthe_2248 phosphoribosyltransferase.
  
  
 0.936
Ccel_0662
HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; hydrolase, HAD-superfamily, subfamily IIIA; HAD superfamily (subfamily IIIA) phosphatase, TIGR01668; PFAM: HAD-superfamily phosphatase subfamily IIIA; KEGG: cth:Cthe_0855 HAD family phosphatase.
 
     0.670
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.645
Ccel_1315
PFAM: type IV pilus assembly PilZ; KEGG: cth:Cthe_0488 type IV pilus assembly PilZ.
  
     0.539
Ccel_1461
KEGG: cth:Cthe_1262 hypothetical protein.
 
     0.486
Ccel_2412
PFAM: type II secretion system protein; KEGG: amt:Amet_3480 type II secretion system protein.
  
  
 0.480
Ccel_2414
PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; KEGG: tte:TTE1262 pili biogenesis protein PilB-like ATPase.
  
  
 0.434
Ccel_2411
KEGG: tte:TTE1265 hypothetical protein.
  
  
 0.420
Ccel_2561
TIGRFAM: rod shape-determining protein MreD; KEGG: cth:Cthe_0090 hypothetical protein.
  
     0.412
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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