STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_0708Putative helix-turn-helix protein YlxM/p13 family protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. (118 aa)    
Predicted Functional Partners:
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.943
Ccel_2240
PFAM: protein of unknown function DUF965; KEGG: cth:Cthe_0151 hypothetical protein; Belongs to the UPF0297 family.
  
     0.738
rpsP
PFAM: ribosomal protein S16; KEGG: cth:Cthe_0769 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
  
    0.676
whiA
Protein of unknown function DUF199; Involved in cell division and chromosome segregation.
  
  
 0.619
polC
DNA polymerase III, alpha subunit; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
     0.604
Ccel_0455
PFAM: protein of unknown function DUF448; KEGG: cth:Cthe_0993 hypothetical protein.
  
    0.579
Ccel_1908
PFAM: protein of unknown function DUF322; KEGG: cth:Cthe_0837 hypothetical protein.
 
     0.512
Ccel_0711
KEGG: cth:Cthe_0768 nucleic acid binding protein; Belongs to the UPF0109 family.
  
  
 0.508
mrnC
Ribonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family.
  
     0.506
Ccel_0707
PFAM: protein of unknown function DUF88; KEGG: fjo:Fjoh_2410 hypothetical protein.
       0.503
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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