Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
celCCFGlycoside hydrolase family 48; Probable endoglucanase involved in the degradation of cellulose or related beta-glucans; Belongs to the glycosyl hydrolase 48 (cellulase L) family. (722 aa)    
Predicted Functional Partners:
celCCG
Glycoside hydrolase family 9; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
   
0.844
Ccel_0379
Protein of unknown function DUF291; PFAM: coagulation factor 5/8 type domain protein; glycoside hydrolase family 5; cellulosome protein dockerin type I; protein of unknown function DUF291; KEGG: cth:Cthe_0821 coagulation factor 5/8 type-like protein.
  
   
 0.749
Ccel_0740
PFAM: glycoside hydrolase family 5; cellulosome protein dockerin type I; KEGG: cth:Cthe_2872 glycoside hydrolase family protein; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
 
 
0.741
Ccel_0739
PFAM: cellulosome protein dockerin type I; FG-GAP repeat protein; KEGG: bld:BLi01376 YesW.
 
 
0.724
Ccel_0728
PFAM: type 3a cellulose-binding domain protein; cellulosome anchoring protein cohesin region; protein of unknown function DUF291; KEGG: cth:Cthe_3077 cellulosome anchoring protein, cohesin region.
 
  
 0.718
Ccel_0734
PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; cellulosome protein dockerin type I; KEGG: hau:Haur_0296 glycoside hydrolase family protein; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
 
0.688
Ccel_1866
PFAM: glycoside hydrolase family 11; KEGG: cpy:Cphy_2105 endo-1,4-beta-xylanase; Belongs to the glycosyl hydrolase 11 (cellulase G) family.
  
   
 0.666
Ccel_0153
PFAM: glycoside hydrolase family 10; KEGG: csc:Csac_0204 glycoside hydrolase family protein.
  
 
 
 0.655
Ccel_2395
PFAM: lipolytic protein G-D-S-L family; cellulosome protein dockerin type I; KEGG: gvi:gll2764 unknown protein.
  
 
 0.642
Ccel_0732
PFAM: glycoside hydrolase family 9; cellulosome protein dockerin type I; Carbohydrate-binding CenC domain protein; glycoside hydrolase family 9 domain protein Ig domain protein; KEGG: cac:CAC0561 cellulase CelE-like protein; Belongs to the glycosyl hydrolase 9 (cellulase E) family.
 
 
0.637
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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