Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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celCCCGlycoside hydrolase family 8; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose. (460 aa)    
Predicted Functional Partners:
Ccel_0728
PFAM: type 3a cellulose-binding domain protein; cellulosome anchoring protein cohesin region; protein of unknown function DUF291; KEGG: cth:Cthe_3077 cellulosome anchoring protein, cohesin region.
 
   
 0.792
celCCA
Glycoside hydrolase family 5; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
  
   
 0.704
Ccel_0254
KEGG: cth:Cthe_2130 hypothetical protein.
  
     0.689
celCCG
Glycoside hydrolase family 9; The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
 
   
0.686
Ccel_1648
PFAM: glycoside hydrolase family 9; type 3a cellulose-binding domain protein; cellulosome protein dockerin type I; KEGG: cth:Cthe_2760 glycoside hydrolase family protein.
  
     0.661
Ccel_0277
PFAM: Fibronectin type III domain protein; KEGG: cth:Cthe_2612 fibronectin, type III.
  
     0.652
Ccel_0755
PFAM: glycoside hydrolase family 9; cellulosome protein dockerin type I; glycoside hydrolase family 9 domain protein Ig domain protein; KEGG: cth:Cthe_0825 glycoside hydrolase family protein.
  
   
 0.640
Ccel_0649
PFAM: cellulosome protein dockerin type I; KEGG: cac:CA_P0119 xylan degradation protein.
  
   
 0.578
Ccel_0592
PFAM: regulatory protein MerR; KEGG: cth:Cthe_0804 MerR family transcriptional regulator.
  
     0.562
Ccel_0429
PFAM: PKD domain containing protein; cellulosome protein dockerin type I; KEGG: cth:Cthe_0624 glycoside hydrolase family protein.
  
     0.554
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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