Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_0954PFAM: PfkB domain protein; KEGG: tpd:Teth39_0632 ribokinase-like domain-containing protein. (321 aa)    
Predicted Functional Partners:
Ccel_2189
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: amt:Amet_0590 alcohol dehydrogenase.
 
 
 0.921
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: cth:Cthe_0217 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.911
pfp
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
   
 0.911
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
   
 0.911
xylA
TIGRFAM: xylose isomerase; PFAM: Xylose isomerase domain protein TIM barrel; KEGG: cdf:CD3064 xylose isomerase; Belongs to the xylose isomerase family.
    
 0.910
Ccel_1029
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cbl:CLK_2861 putative L-iditol 2-dehydrogenase.
  
 
 0.907
Ccel_1179
TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; KEGG: cno:NT01CX_1588 mannose-6-phosphate isomerase, class I.
    
 0.906
Ccel_1007
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cbl:CLK_2861 putative L-iditol 2-dehydrogenase.
  
 
 0.905
Ccel_1030
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pac:PPA0918 putative zinc-binding sorbitol dehydrogenase.
  
 
 0.905
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.903
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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