Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_1045PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; KEGG: fnu:FN0475 MiaB protein. (416 aa)    
Predicted Functional Partners:
Ccel_1044
PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: ctc:CTC01641 putative transcriptional regulatory protein.
 
  
 0.743
Ccel_1043
PFAM: Haloacid dehalogenase domain protein hydrolase type 3; KEGG: cth:Cthe_1482 Cof-like hydrolase.
  
    0.705
Ccel_1041
Hypothetical protein; KEGG: mbn:Mboo_1451 GHMP kinase.
       0.635
Ccel_1042
PFAM: aminotransferase class I and II; KEGG: cdf:CD1549 putative histidinol-phosphate aminotransferase.
       0.627
Ccel_1040
Collagenase and related protease-like protein; KEGG: sso:SSO1759 protease, putative.
  
  
 0.615
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
 
  
 0.596
Ccel_0628
Dinitrogenase iron-molybdenum cofactor biosynthesis protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
   
 0.555
Ccel_1046
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: gme:Gmet_1705 cobalamin B12-binding/radical SAM family protein.
  
    0.503
Ccel_1532
Sun protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. Belongs to the NusB family.
  
  
 0.491
Ccel_1144
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family.
  
 
 0.490
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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