Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_1071PFAM: nickel-dependent hydrogenase large subunit; KEGG: cbb:CLD_2800 [Ni/Fe] hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (470 aa)    
Predicted Functional Partners:
Ccel_1070
TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: cbl:CLK_1224 [Ni/Fe] hydrogenase, small subunit.
 
 0.999
Ccel_1072
TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: cac:CA_P0143 hydrogenase maturation protease delta subunit, HyaD-like.
 
 
 0.977
Ccel_2918
TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; KEGG: amt:Amet_1177 carbon-monoxide dehydrogenase, catalytic subunit.
  
  
 0.915
Ccel_0438
TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; KEGG: cth:Cthe_2801 carbon-monoxide dehydrogenase, catalytic subunit.
     
 0.901
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.899
Ccel_1069
PFAM: cytochrome b5; KEGG: cac:CA_P0144 steroid-binding protein.
 
     0.885
Ccel_0464
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: cac:CAC0811 hydrogenase expression-formation factor (HypD).
 
 
 0.884
Ccel_0463
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: deb:DehaBAV1_1241 hydrogenase assembly chaperone HypC/HupF.
 
 
 0.866
Ccel_0462
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: gsu:GSU0306 hydrogenase maturation protein HypF.
 
 
 
 0.862
Ccel_3363
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: det:DET1431 hydrogenase accessory protein HypB.
 
  
 0.811
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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