STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: aoe:Clos_1330 glutamate-1-semialdehyde-2,1-aminomutase. (434 aa)    
Predicted Functional Partners:
Ccel_1279
PFAM: delta-aminolevulinic acid dehydratase; KEGG: aoe:Clos_1329 delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.998
hemA
Tetrapyrrole biosynthesis, glutamyl-tRNA reductase-like protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.996
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.987
Ccel_1278
TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase.
 
  
 0.971
Ccel_1282
TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1379 precorrin-6x reductase.
     
 0.867
Ccel_1276
TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: aoe:Clos_1326 precorrin-6X reductase.
 
   
 0.860
Ccel_1281
PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: ppd:Ppro_1299 cobalamin (vitamin B12) biosynthesis CbiX protein.
     
 0.837
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
     
 0.836
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
     
 0.827
Ccel_0978
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: amr:AM1_A0228 beta-ketoacyl synthase, putative.
    
 0.824
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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