| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ccel_1271 | Ccel_1272 | Ccel_1271 | Ccel_1272 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | 0.994 |
| Ccel_1271 | Ccel_1273 | Ccel_1271 | Ccel_1273 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cpy:Cphy_1377 cobalamin (vitamin B12) biosynthesis CbiG protein. | 0.994 |
| Ccel_1271 | Ccel_1275 | Ccel_1271 | Ccel_1275 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1378 precorrin-3B C17-methyltransferase. | 0.999 |
| Ccel_1271 | Ccel_1276 | Ccel_1271 | Ccel_1276 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: aoe:Clos_1326 precorrin-6X reductase. | 0.993 |
| Ccel_1271 | Ccel_1282 | Ccel_1271 | Ccel_1282 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1379 precorrin-6x reductase. | 0.992 |
| Ccel_1271 | Ccel_1285 | Ccel_1271 | Ccel_1285 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cpy:Cphy_1382 precorrin-8X methylmutase CbiC/CobH. | 0.989 |
| Ccel_1271 | cbiA | Ccel_1271 | Ccel_1283 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.976 |
| Ccel_1271 | cbiD | Ccel_1271 | Ccel_1270 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.985 |
| Ccel_1271 | cobD | Ccel_1271 | Ccel_1286 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.917 |
| Ccel_1271 | cobQ | Ccel_1271 | Ccel_1284 | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.990 |
| Ccel_1272 | Ccel_1271 | Ccel_1272 | Ccel_1271 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1375 precorrin-2 C20-methyltransferase; Belongs to the precorrin methyltransferase family. | 0.994 |
| Ccel_1272 | Ccel_1273 | Ccel_1272 | Ccel_1273 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | PFAM: cobalamin (vitamin B12) biosynthesis CbiG protein; KEGG: cpy:Cphy_1377 cobalamin (vitamin B12) biosynthesis CbiG protein. | 0.999 |
| Ccel_1272 | Ccel_1275 | Ccel_1272 | Ccel_1275 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1378 precorrin-3B C17-methyltransferase. | 0.999 |
| Ccel_1272 | Ccel_1276 | Ccel_1272 | Ccel_1276 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: aoe:Clos_1326 precorrin-6X reductase. | 0.995 |
| Ccel_1272 | Ccel_1282 | Ccel_1272 | Ccel_1282 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1379 precorrin-6x reductase. | 0.997 |
| Ccel_1272 | Ccel_1285 | Ccel_1272 | Ccel_1285 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: cpy:Cphy_1382 precorrin-8X methylmutase CbiC/CobH. | 0.995 |
| Ccel_1272 | cbiA | Ccel_1272 | Ccel_1283 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.962 |
| Ccel_1272 | cbiD | Ccel_1272 | Ccel_1270 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. | 0.988 |
| Ccel_1272 | cobD | Ccel_1272 | Ccel_1286 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.915 |
| Ccel_1272 | cobQ | Ccel_1272 | Ccel_1284 | TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cpy:Cphy_1376 precorrin-4 C11-methyltransferase. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.985 |