Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_1448KEGG: cth:Cthe_1383 tetratricopeptide TPR_2. (374 aa)    
Predicted Functional Partners:
Ccel_2046
KEGG: cth:Cthe_0470 hypothetical protein.
  
     0.771
Ccel_0277
PFAM: Fibronectin type III domain protein; KEGG: cth:Cthe_2612 fibronectin, type III.
  
     0.763
Ccel_0718
KEGG: cth:Cthe_0760 hypothetical protein.
  
     0.762
Ccel_0728
PFAM: type 3a cellulose-binding domain protein; cellulosome anchoring protein cohesin region; protein of unknown function DUF291; KEGG: cth:Cthe_3077 cellulosome anchoring protein, cohesin region.
  
     0.760
Ccel_2566
PFAM: Negative regulator of genetic competence; KEGG: cth:Cthe_0085 negative regulator of genetic competence.
  
     0.738
Ccel_0042
TIGRFAM: primosome, DnaD subunit; PFAM: DnaD and phage-associated region; KEGG: cth:Cthe_2419 DNA replication protein DnaD.
  
     0.731
Ccel_0509
KEGG: cth:Cthe_1830 hypothetical protein.
  
     0.729
Ccel_0817
PFAM: protein of unknown function DUF402; KEGG: cth:Cthe_2746 hypothetical protein.
  
     0.728
Ccel_0288
Hypothetical protein; KEGG: cth:Cthe_1932 S-layer-like domain-containing protein.
  
     0.713
Ccel_0592
PFAM: regulatory protein MerR; KEGG: cth:Cthe_0804 MerR family transcriptional regulator.
  
     0.709
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.