Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ccel_1534PFAM: Protein phosphatase 2C-like; SMART: protein phosphatase 2C domain protein; KEGG: cth:Cthe_0573 protein serine/threonine phosphatases. (241 aa)    
Predicted Functional Partners:
Ccel_1535
PFAM: tyrosine protein kinase; PASTA domain containing protein; Serine/threonine protein kinase-related; SMART: serine/threonine protein kinase; KEGG: cth:Cthe_0574 serine/threonine protein kinase.
 
 0.991
Ccel_1532
Sun protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. Belongs to the NusB family.
  
  
 0.887
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
   0.884
rsgA
Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
  
  
 0.856
Ccel_0111
PFAM: tyrosine protein kinase; Serine/threonine protein kinase-related; SMART: serine/threonine protein kinase; KEGG: cac:CAC0404 TPR repeat-containing serine/threonin protein kinase.
 
 
 0.844
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family.
  
  
 0.821
Ccel_1537
PFAM: ribulose-phosphate 3-epimerase; KEGG: cth:Cthe_0576 ribulose-5-phosphate 3-epimerase.
  
    0.734
Ccel_2478
PFAM: Forkhead-associated protein; KEGG: cbf:CLI_3569 FHA domain-containing protein.
 
 
 0.713
Ccel_1538
TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase catalytic region; KEGG: cth:Cthe_0577 thiamine pyrophosphokinase.
     
 0.685
Ccel_1531
PFAM: peptidase membrane zinc metallopeptidase putative; KEGG: cth:Cthe_0570 peptidase, membrane zinc metallopeptidase, putative.
  
    0.603
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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