Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nifHNifH/frxC-family protein; The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein; Belongs to the NifH/BchL/ChlL family. (276 aa)    
Predicted Functional Partners:
Ccel_1615
PFAM: oxidoreductase/nitrogenase component 1; KEGG: mac:MA1631 nitrogenase associated protein E.
 
 
 0.996
Ccel_1614
PFAM: oxidoreductase/nitrogenase component 1; KEGG: ckl:CKL_1743 VnfN.
 
 
 0.995
Ccel_2430
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cth:Cthe_0374 glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.916
hcp
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.906
hcp-2
Hybrid cluster protein; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
     
 0.906
Ccel_0561
PFAM: glutamine synthetase catalytic region; KEGG: tpd:Teth39_1666 glutamine synthetase, catalytic region.
     
  0.900
Ccel_1610
PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: paa:Paes_1634 nitrogenase cofactor biosynthesis protein NifB.
 
   
 0.828
Ccel_1617
PFAM: GCN5-related N-acetyltransferase; KEGG: ton:TON_1418 ribosomal protein-alanine acetyltransferase.
 
  
 0.733
Ccel_0628
Dinitrogenase iron-molybdenum cofactor biosynthesis protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
  
  
 0.714
Ccel_1164
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cdf:CD2682 pyruvate-flavodoxin oxidoreductase.
  
  
 0.591
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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