Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_1623PFAM: Cupin 2 conserved barrel domain protein; KEGG: bte:BTH_II0571 pectin degradation protein KdgF. (112 aa)    
Predicted Functional Partners:
Ccel_1624
PFAM: pyruvate carboxyltransferase; KEGG: mth:MTH1630 trans-homoaconitate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
       0.768
Ccel_1625
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: chy:CHY_1732 acyl-CoA dehydrogenase.
  
  
 0.569
leuC-2
Homoaconitate hydratase family protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
    0.500
Ccel_1626
PFAM: AMP-dependent synthetase and ligase; KEGG: vpa:VP2425 putative long-chain-fatty-acid-CoA ligase.
       0.464
Ccel_1620
KEGG: mar:MAE_56560 bacilysin biosynthesis protein BacA-like protein.
  
  
 0.454
Ccel_1144
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: afl:Aflv_0303 multidomain redox protein (NAD(FAD)-dependent oxidoreductase; rhodanese domain; SirA-like redox domain; peroxiredoxin domain); Belongs to the sulfur carrier protein TusA family.
  
    0.436
Ccel_1621
TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: hhe:HH1135 3-isopropylmalate dehydratase; Belongs to the LeuD family.
  
    0.426
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.