Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ccel_1671PFAM: PfkB domain protein; KEGG: cpy:Cphy_0227 ribokinase-like domain-containing protein. (338 aa)    
Predicted Functional Partners:
Ccel_1672
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: cpy:Cphy_0054 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.
 
 0.992
Ccel_3192
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: amt:Amet_1261 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.
 
 0.981
uxuA-2
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.936
Ccel_3191
PFAM: PfkB domain protein; KEGG: ote:Oter_4259 ribokinase-like domain-containing protein.
  
  
 
0.923
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.869
Ccel_1537
PFAM: ribulose-phosphate 3-epimerase; KEGG: cth:Cthe_0576 ribulose-5-phosphate 3-epimerase.
  
 0.842
Ccel_1670
PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: cpe:CPE0147 beta-D-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
 
   
 0.743
Ccel_1673
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cpe:CPE0149 D-mannonate oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 
 
 0.740
uxaC-2
PFAM: Glucuronate isomerase; KEGG: csc:Csac_1949 glucuronate isomerase.
 
   
 0.681
Ccel_1675
TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: cpe:CPE0153 glucuronide permease.
 
  
 0.606
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
Server load: low (28%) [HD]