Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uxaC-2PFAM: Glucuronate isomerase; KEGG: csc:Csac_1949 glucuronate isomerase. (485 aa)    
Predicted Functional Partners:
Ccel_0139
PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: mta:Moth_0429 mannitol dehydrogenase.
 
 
 0.974
uxuA-2
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.964
Ccel_1670
PFAM: glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2 TIM barrel; glycoside hydrolase family 2 sugar binding; KEGG: cpe:CPE0147 beta-D-glucuronidase; Belongs to the glycosyl hydrolase 2 family.
 
  
 0.961
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.911
uxaC
PFAM: Glucuronate isomerase; KEGG: bsu:BSU12300 glucuronate isomerase.
  
  
 
0.905
Ccel_1009
PFAM: aldo/keto reductase; KEGG: sus:Acid_2860 aldehyde reductase.
     
  0.900
Ccel_1675
TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter; PFAM: major facilitator superfamily MFS_1; KEGG: cpe:CPE0153 glucuronide permease.
 
   
 0.885
Ccel_1673
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cpe:CPE0149 D-mannonate oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.839
Ccel_3438
PFAM: glycoside hydrolase family 43; KEGG: oih:OB2087 arabinofuranosidase; Belongs to the glycosyl hydrolase 43 family.
 
  
 0.835
Ccel_1231
Carbohydrate binding family 6; PFAM: cellulosome protein dockerin type I; Carbohydrate binding family 6; glycoside hydrolase family 43; SMART: cellulose binding type IV; KEGG: cth:Cthe_2196 carbohydrate-binding family 6 protein; Belongs to the glycosyl hydrolase 43 family.
    
 0.811
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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