Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Ccel_1692PFAM: Peptidoglycan-binding LysM; KEGG: cth:Cthe_0772 peptidoglycan-binding LysM. (96 aa)    
Predicted Functional Partners:
lexA
SOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.737
Ccel_0254
KEGG: cth:Cthe_2130 hypothetical protein.
  
   0.659
Ccel_0107
PFAM: FlgN family protein; KEGG: cth:Cthe_2216 hypothetical protein.
  
     0.648
Ccel_1356
KEGG: cth:Cthe_2351 hypothetical protein.
  
     0.628
Ccel_1341
PFAM: polysaccharide deacetylase; KEGG: cth:Cthe_0175 polysaccharide deacetylase.
  
   
 0.623
Ccel_2798
PFAM: Accessory gene regulator B; KEGG: cth:Cthe_2358 accessory gene regulator B.
  
     0.610
Ccel_0017
TIGRFAM: spore coat protein, CotS family; KEGG: cth:Cthe_2398 putative spore coat protein.
 
   
 0.598
Ccel_0505
Hypothetical protein; KEGG: cth:Cthe_1337 type II secretion system protein.
  
     0.598
Ccel_2214
KEGG: cth:Cthe_0359 hypothetical protein.
  
     0.597
Ccel_0092
PFAM: Anti-sigma-28 factor FlgM family protein; KEGG: cth:Cthe_2246 anti-sigma-28 factor, FlgM.
  
    0.583
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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