Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Ccel_1698KEGG: cth:Cthe_0778 hypothetical protein; Belongs to the UPF0342 family. (128 aa)    
Predicted Functional Partners:
miaB
RNA modification enzyme, MiaB family; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
       0.757
Ccel_0277
PFAM: Fibronectin type III domain protein; KEGG: cth:Cthe_2612 fibronectin, type III.
  
     0.737
Ccel_0728
PFAM: type 3a cellulose-binding domain protein; cellulosome anchoring protein cohesin region; protein of unknown function DUF291; KEGG: cth:Cthe_3077 cellulosome anchoring protein, cohesin region.
  
     0.737
Ccel_0254
KEGG: cth:Cthe_2130 hypothetical protein.
  
     0.713
Ccel_2169
KEGG: cth:Cthe_3163 carbohydrate-binding family 25 protein.
  
     0.705
Ccel_0024
PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: cth:Cthe_2407 AAA ATPase, central region.
  
     0.688
Ccel_0817
PFAM: protein of unknown function DUF402; KEGG: cth:Cthe_2746 hypothetical protein.
  
     0.676
Ccel_0239
Hypothetical protein; KEGG: LOC100083241; similar to vitellogenin.
  
     0.637
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.607
Ccel_1977
KEGG: cth:Cthe_1036 hypothetical protein.
  
     0.607
Your Current Organism:
Ruminiclostridium cellulolyticum
NCBI taxonomy Id: 394503
Other names: Clostridium cellulolyticum H10, R. cellulolyticum H10, Ruminiclostridium cellulolyticum H10
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